Theoretical Validation of In Chemico Skin Sensitization Assay "ADRA" Using the Products Formed by Nucleophilic Reagents and Chemicals.
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DOI: 10.1021/acs.chemrestox.2c00228
Abstract: Amino acid derivative reactivity assay (ADRA) is an in chemico assay for assessing the skin sensitization potential of chemicals by evaluating the reactivity of nucleophilic reagents that mimic skin proteins. N-(2-(1-Naphthyl)acetyl)-l-cysteine (NAC) and α-N-(2-(1-naphthyl)acetyl)-l-lysine (NAL),… read more here.
Keywords: assay adra; skin; nucleophilic reagents; test ... See more keywords
Promotion of biomass pyrolytic saccharification and lignin depolymerization via nucleophilic reagents quenching of the carbonium ions.
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DOI: 10.2139/ssrn.4163530
Abstract: The condensation of lignin under acidic conditions inhibited the subsequent value-added utilization of lignin, and the condensed lignin covered the biomass surface. Here, a method of benzenesulfonic acid pretreatment combined with nucleophilic reagents that promoted… read more here.
Keywords: lignin; nucleophilic reagents; biomass; carbonium ions ... See more keywords