Sequential Nucleophilic Substitution of the α‐Pyrrole and p‐Aryl Positions of meso‐Pentafluorophenyl‐Substituted BODIPYs
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700264
Abstract: Borondipyrrins (BODIPYs) have found wide-spread application in bioimaging and material sciences. These applications require the tuning of the chemical and photophysical properties of the fluorophore through the introduction of functional groups at the BODIPY core.… read more here.
Keywords: nucleophilic substitution; pentafluorophenyl; substitution pyrrole; substituted bodipys ... See more keywords
NUCLEOPHILIC SUBSTITUTION OF A 4-DIMETHYLAMINO GROUP IN QUINOLINE PROTON SPONGES. STABILIZATION OF 4-QUINOLONES IN HYDROXY FORM. SYNTHESIS OF A PROTON SPONGE BASED ON 8-HYDROXYQUINOLINE
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5301
Abstract: Demethylation of methoxy groups in 6(8)-methoxy-2,4,5-tris(dimethylamino)quinolines with 48% HBr leads to nucleophilic substitution of the 4-NMe2 group with the formation of quinolones existing in solution and the solid state in the hydroxy form stabilized by… read more here.
Keywords: nucleophilic substitution; dimethylamino; hydroxy form; group ... See more keywords
Nucleophilic substitution reactions of 1-methyl-4,5-dinitroimidazole with aqueous ammonia or sodium azide
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2389-5
Abstract: In this work, 5-amino-1-methyl-4-nitroimidazole was synthesized by amination reaction of 1-methyl-4,5-dinitroimidazole with aqueous ammonia in 95% yield. Meanwhile, one of its isomers, 4-amino-1-methyl-5-nitroimidazole as byproduct was obtained from the filtrate. Furthermore, nucleophilic substitution reaction of… read more here.
Keywords: methyl dinitroimidazole; dinitroimidazole aqueous; nucleophilic substitution; aqueous ammonia ... See more keywords
Nucleophilic substitution of a 4-dimethylamino group in quinoline proton sponges. Stabilization of 4-quinolones in hydroxy form. Synthesis of a proton sponge based on 8-hydroxyquinoline
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02587-2
Abstract: Demethylation of methoxy groups in 6(8)-methoxy-2,4,5-tris(dimethylamino)quinolines with 48% HBr leads to nucleophilic substitution of the 4-NMe2 group with the formation of quinolones existing in solution and the solid state in the hydroxy form stabilized by… read more here.
Keywords: nucleophilic substitution; dimethylamino; hydroxy form; group ... See more keywords
Magnetic hydroxyapatite-immobilized 1,4-diazabicyclo [2.2.2] octane as a highly efficient and eco-friendly nanocatalyst for the promotion of nucleophilic substitution reactions of benzyl halides under green conditions
Sign Up to like & getrecommendations! Published in 2017 at "Reaction Kinetics, Mechanisms and Catalysis"
DOI: 10.1007/s11144-017-1276-x
Abstract: The synthesized magnetic inorganic–organic hybrid nanocomposite, used as a phase-transfer catalyst on the mesoporous substrate in this paper, provides a green and efficient catalytic system for nucleophilic substitution reactions of benzyl halides in water. The… read more here.
Keywords: nucleophilic substitution; microscopy; substitution reactions; spectroscopy ... See more keywords
Asymmetric identity SN2 transition states: Nucleophilic substitution at α-substituted carbon and silicon centers
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Mass Spectrometry"
DOI: 10.1016/j.ijms.2016.06.003
Abstract: We have quantum chemically investigated the archetypal nucleophilic substitution reactions at carbon (SN2@C) and at silicon (SN2@Si) in the model reaction systems Cl− + A(CH3)2(CH2X)Cl (A = C, Si; X = H, F, Cl, Br,… read more here.
Keywords: nucleophilic substitution; transition; silicon; identity ... See more keywords
Dual reactivity of 1-chloro- and 1-bromo-3,5-dinitrobenzenes in aromatic nucleophilic substitution
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DOI: 10.1016/j.mencom.2017.03.018
Abstract: Aromatic nucleophilic substitution reactions in 1-halo-3,5-dinitrobenzenes (where the halogen is bromine or chlorine) can occur with replacement of either a nitro group or a halogen atom, depending on the nature of anionic nucleophile Nu– as… read more here.
Keywords: nucleophilic substitution; chloro bromo; dual reactivity; aromatic nucleophilic ... See more keywords
Synthesis and DFT studies of novel aryloxymaleimides via nucleophilic substitution of tosyloxy group
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.04.020
Abstract: Abstract Maleimide skeleton distributes widely in a great many substances, and maleimides are very useful building blocks in organic synthesis and many related disciplines, like bioconjugation. As an excellent leaving group, tosyloxy (-OTs) group are… read more here.
Keywords: synthesis; tosyloxy group; nucleophilic substitution; reaction ... See more keywords
Nucleophilic substitution of 4-bromomethyltriazolium with different nucleophiles
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DOI: 10.1016/j.tet.2018.10.009
Abstract: Abstract 1,2,3-Triazolium salts draw much attentions in recent years. We developed a new synthetic method to heteroatom-functionalized triazoliums via nucleophilic substitution of 4-bromomethyltriazolium. This method afforded triazoliums with different S , N , and O… read more here.
Keywords: different nucleophiles; nucleophilic substitution; bromomethyltriazolium different; substitution bromomethyltriazolium ... See more keywords
Exploring Mechanisms of Biotic Chlorinated Alkane Reduction: Evidence of Nucleophilic Substitution (SN2) with Vitamin B12.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.1c06066
Abstract: Chlorinated alkanes are notorious groundwater contaminants. Their natural reductive dechlorination by microorganisms involves reductive dehalogenases (RDases) containing cobamide as a cofactor. However, underlying mechanisms of reductive dehalogenation have remained uncertain. Here, observed products, radical trap… read more here.
Keywords: cobalamin; sn2; nucleophilic substitution; substitution sn2 ... See more keywords
Direct Amination of Cobaltocenium Hexafluoridophosphate via Vicarious Nucleophilic Substitution
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DOI: 10.1021/acs.organomet.9b00205
Abstract: In this communication we report a convenient, as short as possible synthesis of aminocobaltocenium hexafluoridophosphate, a very useful compound for further functionalization in cobaltocenium chemistry. Via vicarious nucleophilic substitution of hydrogen of cobaltocenium hexafluoridophosphate with… read more here.
Keywords: vicarious nucleophilic; hexafluoridophosphate; via vicarious; nucleophilic substitution ... See more keywords