Articles with "nucleoside modified" as a keyword



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Nucleoside-Modified mRNA-Based Influenza Vaccines Circumvent Problems Associated with H3N2 Vaccine Strain Egg Adaptation

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Published in 2022 at "Journal of Virology"

DOI: 10.1128/jvi.01723-22

Abstract: This study shows that the nucleoside-modified mRNA-LNP vaccine platform is a promising alternative for egg-based influenza vaccines. We show that mRNA-LNP vaccines expressing H3 antigens elicit high levels of antibodies in mice and protect against… read more here.

Keywords: egg; nucleoside modified; egg based; modified mrna ... See more keywords
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Herpes Zoster Following a Nucleoside-Modified Messenger RNA COVID-19 Vaccine.

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Published in 2022 at "Cutis"

DOI: 10.12788/cutis.0423

Abstract: Herpes zoster (HZ) was suspected as a predictive cutaneous manifestation of COVID-19, with a debated prognostic significance. We report a series of 5 cases of HZ occurring after vaccination with a nucleoside-modified messenger RNA (mRNA)… read more here.

Keywords: messenger rna; nucleoside modified; covid; herpes zoster ... See more keywords
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Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury

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Published in 2023 at "Research"

DOI: 10.34133/research.0056

Abstract: Efficient in vivo delivery of anti-inflammatory proteins to modulate the microenvironment of an injured spinal cord and promote neuroprotection and functional recovery is a great challenge. Nucleoside-modified messenger RNA (mRNA) has become a promising new… read more here.

Keywords: encoding nucleoside; nucleoside modified; spinal cord; injury ... See more keywords