Articles with "nucleoside phosphoramidite" as a keyword



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Improved Metal-Free Approach for the Synthesis of Protected Thiol Containing Thymidine Nucleoside Phosphoramidite and Its Application for the Synthesis of Ligatable Oligonucleotide Conjugates

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Published in 2023 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics15010248

Abstract: Oligonucleotide conjugates are versatile scaffolds that can be applied in DNA-based screening platforms and ligand display or as therapeutics. Several different chemical approaches are available for functionalizing oligonucleotides, which are often carried out on the… read more here.

Keywords: application; ligatable oligonucleotide; synthesis; nucleoside phosphoramidite ... See more keywords