Synthesis, antiviral, DFT and molecular docking studies of some novel 1,2,4-triazine nucleosides as potential bioactive compounds.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate research"
DOI: 10.1016/j.carres.2021.108246
Abstract: A novel series of nucleosides with potential antiviral activity have been synthesized and characterized using IR, MS, 1D NMR and 2D NMR data. The antiviral activity of the synthesized compounds was assessed against the Coxsackie… read more here.
Keywords: nucleosides potential; synthesis antiviral; dft molecular; docking studies ... See more keywords
Novel nucleosides as potential inhibitors of fungal lanosterol 14α-demethylase: an in vitro and in silico study.
Sign Up to like & getrecommendations! Published in 2019 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2019-0014
Abstract: Aim: The global burden of fungal infections has transitioned from a case-specific observation to a major cause of high human mortality. Therefore, novel compounds with innovative methodologies need to be synthesized and evaluated for their… read more here.
Keywords: potential inhibitors; nucleosides potential; fungal lanosterol; novel nucleosides ... See more keywords