The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis
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DOI: 10.1038/s41556-019-0388-0
Abstract: Chromosome translocation is a major cause of the onset and progression of diverse types of cancers. However, the mechanisms underlying this process remain poorly understood. Here, we identified a non-homologous end-joining protein, IFFO1, which structurally… read more here.
Keywords: nucleoskeleton; chromosome translocation; iffo1; broken dna ... See more keywords