High-mobility group nucleosome binding domain 1 (HMGN1) functions as a Th1-polarizing alarmin.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in immunology"
DOI: 10.1016/j.smim.2018.02.012
Abstract: High-mobility group (HMG) nucleosome binding domain 1 (HMGN1), which previously was thought to function only as a nucleosome-binding protein that regulates chromatin structure, histone modifications, and gene expression, was recently discovered to be an alarmin… read more here.
Keywords: binding domain; high mobility; nucleosome binding; mobility group ... See more keywords
Nucleosome binding by the pioneer transcription factor OCT4
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DOI: 10.1038/s41598-020-68850-1
Abstract: Transcription factor binding to genomic DNA is generally prevented by nucleosome formation, in which the DNA is tightly wrapped around the histone octamer. In contrast, pioneer transcription factors efficiently bind their target DNA sequences within… read more here.
Keywords: pioneer transcription; transcription; oct4; nucleosome binding ... See more keywords