Nucleosome organization of mouse embryos during pre-implantation development
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DOI: 10.1038/s41598-025-05642-5
Abstract: Sexual reproduction begins with sperm–oocyte fusion to form a zygote, where chromatin undergoes dramatic reorganization to establish totipotency. Although nucleosomes- the basic units of eukaryotic chromatin and key epigenetic regulators- are extensively remodeled during early… read more here.
Keywords: nucleosome organization; pre implantation; organization mouse; embryos pre ... See more keywords
NucHMM: a method for quantitative modeling of nucleosome organization identifying functional nucleosome states distinctly associated with splicing potentiality
Sign Up to like & getrecommendations! Published in 2021 at "Genome Biology"
DOI: 10.1186/s13059-021-02465-1
Abstract: We develop a novel computational method, NucHMM, to identify functional nucleosome states associated with cell type-specific combinatorial histone marks and nucleosome organization features such as phasing, spacing and positioning. We test it on publicly available… read more here.
Keywords: distinctly associated; states distinctly; functional nucleosome; nucleosome states ... See more keywords
A comparison of nucleosome organization in Drosophila cell lines
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DOI: 10.1371/journal.pone.0178590
Abstract: Changes in the distribution of nucleosomes along the genome influence chromatin structure and impact gene expression by modulating the accessibility of DNA to transcriptional machinery. However, the role of genome-wide nucleosome positioning in gene expression… read more here.
Keywords: drosophila; cell lines; gene expression; cell ... See more keywords