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Published in 2020 at "BioEssays"
DOI: 10.1002/bies.201900234
Abstract: Chromatin structure and dynamics regulate key cellular processes such as DNA replication, transcription, repair, remodeling, and gene expression, wherein different protein factors interact with the nucleosomes. In these events, DNA and RNA polymerases, chromatin remodeling…
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Keywords:
structural basis;
basis nucleosome;
dna;
nucleosome recognition ... See more keywords
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Published in 2021 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2021.05.006
Abstract: The recent torrent of structures of chromatin complexes determined by cryoelectron microscopy provides an opportunity to discern general principles for how chromatin factors and enzymes interact with their nucleosome substrate. We find that many chromatin…
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Keywords:
factors enzymes;
recognition chromatin;
chromatin factors;
chromatin ... See more keywords
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Published in 2018 at "Science"
DOI: 10.1126/science.aar2781
Abstract: Recognizing centromere by kinetochore The kinetochore proteins CENP-N and CENP-C recognize the histone H3 variant CENP-A in the centromeric nucleosome. This ensures proper kinetochore assembly and accurate segregation of chromosomes. Chittori et al. describe the…
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Keywords:
microscopy;
centromeric nucleosome;
cenp;
cenp cenp ... See more keywords