Articles with "nucleotide chemical" as a keyword



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iDNA4mC: identifying DNA N4‐methylcytosine sites based on nucleotide chemical properties

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Published in 2017 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btx479

Abstract: Motivation DNA N4‐methylcytosine (4mC) is an epigenetic modification. The knowledge about the distribution of 4mC is helpful for understanding its biological functions. Although experimental methods have been proposed to detect 4mC sites, they are expensive… read more here.

Keywords: nucleotide chemical; 4mc sites; chemical properties; dna methylcytosine ... See more keywords
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Identification of D Modification Sites Using a Random Forest Model Based on Nucleotide Chemical Properties

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23063044

Abstract: Dihydrouridine (D) is an abundant post-transcriptional modification present in transfer RNA from eukaryotes, bacteria, and archaea. D has contributed to treatments for cancerous diseases. Therefore, the precise detection of D modification sites can enable further… read more here.

Keywords: modification; identification modification; nucleotide chemical; random forest ... See more keywords