Development of a Transcriptional Activator‐Like Effector Protein to Accurately Discriminate Single Nucleotide Difference
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DOI: 10.1002/cbic.202200486
Abstract: Transcriptional activator‐like effector (TALE), a DNA‐binding protein, is widely used in genome editing. However, the recognition of the target sequence by the TALE is adversely affected by the number of mismatches. Therefore, the association constant… read more here.
Keywords: activator like; nucleotide difference; transcriptional activator; nucleotide ... See more keywords