Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice
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DOI: 10.1038/s41401-020-00537-9
Abstract: Remdesivir (RDV) exerts anti-severe acute respiratory coronavirus 2 activity following metabolic activation in the target tissues. However, the pharmacokinetics and tissue distributions of the parent drug and its active metabolites have been poorly characterized to… read more here.
Keywords: rdv; nucleotide monophosphate; triphosphate; remdesivir ... See more keywords