High levels of resistance to nucleoside/nucleotide reverse transcriptase inhibitors in newly-diagnosed antiretroviral treatment naive children in sub-Saharan Africa.
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DOI: 10.1097/qad.0000000000002580
Abstract: : Exposure of infants to antiretroviral drugs for prevention of mother-to-child transmission can induce resistance to nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs). Data from nine national surveys of pretreatment drug resistance in children newly diagnosed with… read more here.
Keywords: nucleoside nucleotide; nucleotide reverse; treatment; resistance ... See more keywords
Nucleotide Reverse Transcriptase Inhibitors: A Thorough Review, Present Status and Future Perspective as HIV Therapeutics.
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DOI: 10.2174/1570162x15666171120110145
Abstract: BACKGROUND Human immunodeficiency virus type-1 (HIV-1) infection leads to acquired immunodeficiency syndrome (AIDS), a severe viral infection that has claimed approximately 658,507 lives in the US between the years 2010-2014. Antiretroviral (ARV) therapy has proven… read more here.
Keywords: transcriptase inhibitors; hiv; infection; pharmacology ... See more keywords