Repetitive Batch Mode Facilitates Enzymatic Synthesis of the Nucleotide Sugars UDP-Gal, UDP-GlcNAc, and UDP-GalNAc on a Multi-Gram Scale.
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology journal"
DOI: 10.1002/biot.201800386
Abstract: The availability of nucleotide sugars is considered as bottleneck for Leloir-glycosyltransferases mediated glycan synthesis. A breakthrough for the synthesis of nucleotide sugars is the development of salvage pathway like enzyme cascades with high product yields… read more here.
Keywords: repetitive batch; batch mode; nucleotide sugars; synthesis ... See more keywords
Mad moves of the building blocks – nucleotide sugars find unexpected paths into cell walls
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/ery026
Abstract: This article comments on: Zhao X, Liu N, Shang N, et al. 2018. Three UDP-xylose transporters (UXTs) participate in xylan biosynthesis by conveying cytosolic UDP-xylose into the Golgi lumen in Arabidopsis. Journal of Experimental Botany… read more here.
Keywords: botany; moves building; building blocks; blocks nucleotide ... See more keywords
Delivery of Nucleotide Sugars to the Mammalian Golgi: A Very Well (un)Explained Story
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158648
Abstract: Nucleotide sugars (NSs) serve as substrates for glycosylation reactions. The majority of these compounds are synthesized in the cytoplasm, whereas glycosylation occurs in the endoplasmic reticulum (ER) and Golgi lumens, where catalytic domains of glycosyltransferases… read more here.
Keywords: delivery nucleotide; nucleotide sugars; golgi well; sugars mammalian ... See more keywords