Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications
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DOI: 10.3390/molecules26113100
Abstract: The click azide = alkyne 1,3-dipolar cycloaddition (click chemistry) has become the approach of choice for bioconjugations in medicinal chemistry, providing facile reaction conditions amenable to both small and biological molecules. Many nucleoside analogs are… read more here.
Keywords: nucleic acids; chemistry; azide alkyne; nucleotides nucleic ... See more keywords
Tellurium-Modified Nucleosides, Nucleotides, and Nucleic Acids with Potential Applications
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DOI: 10.3390/molecules27238379
Abstract: Tellurium was successfully incorporated into proteins and applied to protein structure determination through X-ray crystallography. However, studies on tellurium modification of DNA and RNA are limited. This review highlights the recent development of Te-modified nucleosides,… read more here.
Keywords: nucleotides nucleic; tellurium; potential applications; nucleosides nucleotides ... See more keywords