Estrogen receptors observed at extranuclear neuronal sites and in glia in the nucleus accumbens core and shell of the female rat: Evidence for localization to catecholaminergic and GABAergic neurons
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25320
Abstract: Estrogens affect dopamine‐dependent diseases/behavior and have rapid effects on dopamine release and receptor availability in the nucleus accumbens (NAc). Low levels of nuclear estrogen receptor (ER) α and ERβ are seen in the NAc, which… read more here.
Keywords: localization; gper1; gabaergic neurons; core shell ... See more keywords
Nucleus accumbens projections: Validity and reliability of fiber reconstructions based on high-resolution diffusion-weighted MRI.
Sign Up to like & getrecommendations! Published in 2021 at "Human brain mapping"
DOI: 10.1002/hbm.25657
Abstract: Clinical effects of deep brain stimulation are largely mediated by the activation of myelinated axons. Hence, increasing attention has been paid in the past on targeting white matter tracts in addition to gray matter. Aims… read more here.
Keywords: accumbens projections; validity reliability; fiber; projections validity ... See more keywords
Corticostriatal plasticity in the nucleus accumbens core
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24494
Abstract: Small fluctuations in striatal glutamate and dopamine are required to establish goal‐directed behaviors and motor learning, while large changes appear to underlie many neuropsychological disorders, including drug dependence and Parkinson's disease. A better understanding of… read more here.
Keywords: dopamine; release; drug; nucleus accumbens ... See more keywords
Neurogranin Regulates Alcohol Sensitivity through AKT Pathway in the Nucleus Accumbens
Sign Up to like & getrecommendations! Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201900266
Abstract: Dysfunction of glutamate neurotransmission in the nucleus accumbens (NAc) has been implicated in the pathophysiology of alcohol use disorders (AUD). Neurogranin (Ng) is exclusively expressed in the brain and mediates N‐methyl‐d‐aspartate receptor (NMDAR) hypo‐function by… read more here.
Keywords: null mice; alcohol sensitivity; nucleus accumbens; mice ... See more keywords
Dissecting Mechanisms of Motivation within the Nucleus Accumbens Using Optogenetics.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0830-2_19
Abstract: Studies mapping psychological functions to discrete brain regions often require manipulations that yield changes in a particular area and observing a subsequent shift in behavior. As investigators tap into neural underpinnings of behavior, it is… read more here.
Keywords: using optogenetics; mechanisms motivation; motivation within; dissecting mechanisms ... See more keywords
Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4601-1
Abstract: RationaleSelf-report studies indicate that cannabis could increase sexual desire in some users. We hypothesized that intoxication increases activation of brain areas responsive to visual erotica, which could be useful in the treatment of hypoactive sexual… read more here.
Keywords: response; intoxication; group; study ... See more keywords
Dose-dependent effects of estrogen on prediction error related neural activity in the nucleus accumbens of healthy young women
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-019-05409-7
Abstract: Rationale Whereas the effect of the sex steroid 17-beta-estradiol (E2) on dopaminergic (DA) transmission in the nucleus accumbens (NAc) is well evidenced in female rats, studies in humans are inconsistent. Moreover, linear and inverted u-shaped… read more here.
Keywords: dose response; neural activity; young women; nucleus accumbens ... See more keywords
Role of dopamine projections from ventral tegmental area to nucleus accumbens and medial prefrontal cortex in reinforcement behaviors assessed using optogenetic manipulation
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-017-0023-3
Abstract: Dopamine (DA) neurons in the ventral tegmental area (VTA) are predicted to play important roles in reward. In pharmacological studies, the rewarding effects of methamphetamine are mediated by DA neurons localized in the VTA. The… read more here.
Keywords: tegmental area; cortex; nac core; ventral tegmental ... See more keywords
Projections from D2 Neurons in Different Subregions of Nucleus Accumbens Shell to Ventral Pallidum Play Distinct Roles in Reward and Aversion.
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience bulletin"
DOI: 10.1007/s12264-021-00632-9
Abstract: The nucleus accumbens shell (NAcSh) plays an important role in reward and aversion. Traditionally, NAc dopamine receptor 2-expressing (D2) neurons are assumed to function in aversion. However, this has been challenged by recent reports which… read more here.
Keywords: accumbens shell; aversion; projections neurons; reward aversion ... See more keywords
Effects of chemogenetic manipulation of the nucleus accumbens core in male C57BL/6J mice.
Sign Up to like & getrecommendations! Published in 2020 at "Alcohol"
DOI: 10.1016/j.alcohol.2020.10.005
Abstract: Binge drinking is a widespread public health concern with limited effective treatment options. To better select pharmaceutical targets, it is imperative to expand our knowledge of the underlying neural mechanisms involved in binge drinking. Our… read more here.
Keywords: nac core; nucleus accumbens; mice; activity ... See more keywords
Facebook usage on smartphones and gray matter volume of the nucleus accumbens
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.04.035
Abstract: &NA; A recent study has implicated the nucleus accumbens of the ventral striatum in explaining why online‐users spend time on the social network platform Facebook. Here, higher activity of the nucleus accumbens was associated with… read more here.
Keywords: facebook usage; volume nucleus; gray matter; matter volume ... See more keywords