A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/s41586-019-1786-y
Abstract: All viruses require strategies to inhibit or evade the immune pathways of cells that they infect. The viruses that infect bacteria, bacteriophages (phages), must avoid immune pathways that target nucleic acids, such as CRISPR–Cas and… read more here.
Keywords: restriction; crispr cas; phage; compartment ... See more keywords
Structural studies of the nucleus-like assembly of jumbo bacteriophage 201φ2-1
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1170112
Abstract: The jumbo phages encode proteins that assemble to form a nucleus-like compartment in infected cells. Here we report the cryo-EM structure and biochemistry characterization of gp105, a protein that is encoded by the jumbo phage… read more here.
Keywords: nucleus like; like assembly; assemble form; like compartment ... See more keywords