Nucleus-targeting near-infrared nanoparticles based on TAT peptide-conjugated IR780 for photo-chemotherapy of breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.122458
Abstract: Abstract Breast cancer is the most common malignant tumor in women. Phototherapy, mainly including photothermal therapy (PTT) and photodynamic therapy (PDT), shows many advantages such as high spatial selectivity, noninvasive nature, and negligible drug resistance… read more here.
Keywords: chemotherapy; cancer; breast cancer; nucleus targeting ... See more keywords
A Nucleus-Targeting DNA Aptamer for Dead Cell Indication.
Sign Up to like & getrecommendations! Published in 2019 at "ACS sensors"
DOI: 10.1021/acssensors.9b00342
Abstract: Dead cells always accompany with live cells in vivo and in cell culture. It is important to distinguish dead cells from live cells in various biological studies. Currently, the probes for dead cells are mainly… read more here.
Keywords: nucleus targeting; targeting dna; live cells; dead cells ... See more keywords
pH/enzyme dual sensitive and nucleus-targeting dendrimer nanoparticles to enhance the antitumour activity of doxorubicin
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2055569
Abstract: Abstract Direct delivery of drugs into the nucleus is a promising nanotechnology therapy, since the nucleus is one of the most important organelles controlling cell proliferation and apoptosis. Here, we report a nucleus-targeting nanocarrier for… read more here.
Keywords: dual sensitive; peg; pamam; nucleus targeting ... See more keywords
Nucleus-Targeting Phototherapy Nanodrugs for High-Effective Anti-Cancer Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.905375
Abstract: DNA is always one of the most important targets for cancer therapy due to its leading role in the proliferation of cancer cells. Phototherapy kills cancer cells by generating reactive oxygen species (ROS) and local… read more here.
Keywords: phototherapy; nucleus targeting; treatment; phototherapy nanodrugs ... See more keywords
Nucleus-Targeting Nanoplatform Based on Dendritic Peptide for Precise Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Polymers"
DOI: 10.3390/polym15071753
Abstract: Photothermal therapy directly acting on the nucleus is a potential anti-tumor treatment with higher killing efficiency. However, in practical applications, it is often difficult to achieve precise nuclear photothermal therapy because agents are difficult to… read more here.
Keywords: photothermal therapy; therapy; dendritic peptide; nucleus targeting ... See more keywords