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Published in 2021 at "Protein & Cell"
DOI: 10.1007/s13238-021-00852-9
Abstract: The hippocampus plays a crucial role in learning and memory, and its progressive deterioration with age is functionally linked to a variety of human neurodegenerative diseases. Yet a systematic profiling of the aging effects on…
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Keywords:
single nucleus;
nucleus transcriptomic;
primate hippocampal;
hippocampal aging ... See more keywords
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Published in 2024 at "Scientific Data"
DOI: 10.1038/s41597-024-04117-y
Abstract: Parkinson’s Disease (PD) is a debilitating neurodegenerative disorder, characterized by motor and cognitive impairments, that affects >1% of the population over the age of 60. The pathogenesis of PD is complex and remains largely unknown.…
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Keywords:
region single;
disease;
multi region;
nucleus transcriptomic ... See more keywords
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Published in 2022 at "National Science Review"
DOI: 10.1093/nsr/nwac147
Abstract: Abstract The process of domestication has led to dramatic differences in behavioral traits between domestic dogs and gray wolves. Whole-genome research found that a class of putative positively selected genes were related to various aspects…
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Keywords:
atlas dog;
domestication;
cell;
transcriptomic atlas ... See more keywords
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Published in 2022 at "Protein & cell"
DOI: 10.1093/procel/pwac057
Abstract: The testis is pivotal for male reproduction, and its progressive functional decline in aging is associated with infertility. However, the regulatory mechanism underlying primate testicular aging remains largely elusive. Here, we resolve the aging-related cellular…
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Keywords:
cell;
single nucleus;
primate testicular;
nucleus transcriptomic ... See more keywords