Key Role of TFEB Nucleus Translocation for Silver Nanoparticle-Induced Cytoprotective Autophagy.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201703711
Abstract: Transcription factor EB (TFEB) is a master regulator of autophagy and lysosomal biogenesis. Here, silver nanoparticles (Ag NPs)-induced cytoprotective autophagy required TFEB is shown. Ag NPs-induced nucleus translocation of TFEB through a well-established mechanism involving… read more here.
Keywords: nucleus translocation; cytoprotective autophagy; induced cytoprotective; autophagy ... See more keywords
Traceable in-cell synthesis and cytoplasm-to-nucleus translocation of a zinc Schiff base complex as a simple and economical anticancer strategy.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc03480c
Abstract: We have proposed a facile and cheap cancer therapeutic strategy by in-cell synthesizing theranostic Zn Schiff base complexes with nuclear targeting and DNA damaging capability. The in-cell synthesis can be traced via a green-to-blue fluorescence… read more here.
Keywords: cytoplasm nucleus; nucleus translocation; cell synthesis; strategy ... See more keywords