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Published in 2018 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-018-4134-2
Abstract: PurposeTo create new immunodeficient Royal College of Surgeons (RCS) rats by introducing the defective MerTK gene into athymic nude rats.MethodsFemale homozygous RCS (RCS-p+/RCS-p+) and male nude rats (Hsd:RH-Foxn1mu, mutation in the foxn1 gene; no T…
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Keywords:
new immunodeficient;
human derived;
transplantation;
derived cells ... See more keywords
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Published in 2023 at "Cell Transplantation"
DOI: 10.1177/09636897231167323
Abstract: Subcutaneous implants of device-encapsulated stem cell–derived pancreatic endoderm (PE) can establish a functional beta cell mass (FBM) with metabolic control in immune-compromised mice. In a study with human-induced pluripotent stem cell-PE, this outcome was favored…
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Keywords:
cell;
beta;
derived pancreatic;
nude rats ... See more keywords
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Published in 2020 at "Comparative medicine"
DOI: 10.30802/aalas-cm-19-000079
Abstract: Cell therapy has shown potential in the field of peripheral nerve repair, and research using rodents is a critical and essentialstep toward clinical development of this approach. Traditionally, most experimental peripheral nerve injuries are conductedin…
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Keywords:
behavioral assessment;
nerve injury;
nude rats;
peripheral nerve ... See more keywords