Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism
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DOI: 10.1371/journal.pone.0180241
Abstract: Dihydroneopterin triphosphate pyrophosphatase (DHNTPase), a member of the Mg2+ dependent Nudix hydrolase superfamily, is the recently-discovered enzyme that functions in the second step of the pterin branch of the folate biosynthetic pathway in E. coli.… read more here.
Keywords: metal; triphosphate pyrophosphatase; nudix hydrolase; dihydroneopterin triphosphate ... See more keywords
PpNUDX8, a Peach NUDIX Hydrolase, Plays a Negative Regulator in Response to Drought Stress
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DOI: 10.3389/fpls.2021.831883
Abstract: Drought stress is a serious abiotic stress source that affects the growth and fruit quality of peach trees. However, the molecular mechanism of the NUDIX hydrolase family in peaches in response to drought stress is… read more here.
Keywords: drought; stress; peach; nudix hydrolase ... See more keywords
Rice Nudix Hydrolase OsNUDX2 Sanitizes Oxidized Nucleotides
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DOI: 10.3390/antiox11091805
Abstract: Nudix hydrolase (NUDX) hydrolyzes 8-oxo-(d)GTP to reduce the levels of oxidized nucleotides in the cells. 8-oxo-(d)GTP produced by reactive oxygen species (ROS) is incorporated into DNA/RNA and mispaired with adenine, causing replicational and transcriptional errors.… read more here.
Keywords: osnudx2 gene; oxidized nucleotides; oxo dgtp; osnudx2 ... See more keywords