Redox active or thiol reactive? Optimization of rapid screens to identify less evident nuisance compounds.
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DOI: 10.1016/j.drudis.2022.03.008
Abstract: Compounds that exhibit assay interference or undesirable mechanisms of bioactivity are routinely encountered in assays at various stages of drug discovery. We observed that assays for the investigation of thiol-reactive and redox-active compounds have not… read more here.
Keywords: active thiol; thiol reactive; nuisance compounds; redox active ... See more keywords