Null alleles and sequence variations at primer binding sites of STR loci within multiplex typing systems.
Sign Up to like & getrecommendations! Published in 2018 at "Legal medicine"
DOI: 10.1016/j.legalmed.2017.10.007
Abstract: Rare variants are widely observed in human genome and sequence variations at primer binding sites might impair the process of PCR amplification resulting in dropouts of alleles, named as null alleles. In this study, 5… read more here.
Keywords: typing systems; null alleles; primer binding; sequence variations ... See more keywords
Microsatellite null alleles affected population genetic analyses: a case study of Maire yew (Taxus chinensis var. mairei)
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Forest Research"
DOI: 10.1080/13416979.2019.1634230
Abstract: ABSTRACT Microsatellite markers are widely used in population genetic analyses. However, the common occurrence of null alleles and their effect on population parameters such as observed heterozygosity, genetic differentiation coefficient, etc., needs to be addressed.… read more here.
Keywords: null alleles; genetic analyses; population genetic; maire yew ... See more keywords
CRISPR-induced null alleles show that Frost protects Drosophila melanogaster reproduction after cold exposure
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Experimental Biology"
DOI: 10.1242/jeb.160176
Abstract: ABSTRACT The ability to survive and reproduce after cold exposure is important in all kingdoms of life. However, even in a sophisticated genetic model system like Drosophila melanogaster, few genes have been identified as functioning… read more here.
Keywords: null alleles; reproduction; cold exposure; tolerance ... See more keywords
The effects of microchipping C57BL/6N mice on standard phenotyping tests.
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DOI: 10.12688/f1000research.21633.1
Abstract: The C57BL/6N inbred lines of mice are widely used in genetic research. They are particularly favoured in large scale studies such as the International Mouse Phenotyping Consortium (IMPC), where C57BL/6N mice are genetically altered to… read more here.
Keywords: phenotyping tests; null alleles; c57bl mice; standard phenotyping ... See more keywords
The effects of microchipping C57BL/6N mice on standard phenotyping tests
Sign Up to like & getrecommendations! Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.21633.2
Abstract: The C57BL/6N inbred lines of mice are widely used in genetic research. They are particularly favoured in large scale studies such as the International Mouse Phenotyping Consortium (IMPC), where C57BL/6N mice are genetically altered to… read more here.
Keywords: phenotyping tests; null alleles; c57bl mice; standard phenotyping ... See more keywords