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Published in 2020 at "Toxicology"
DOI: 10.1016/j.tox.2020.152521
Abstract: Homeobox (Hox) genes encode homeodomain proteins, which play important roles in the development and morphological diversification of organisms including plants and animals. Perfluorinated chemicals (PFCs), which are well recognized industrial pollutants and universally detected in…
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Keywords:
mouse livers;
null mouse;
hox;
mrna expression ... See more keywords
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Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.242701
Abstract: ABSTRACT The RNA-binding protein LIN28A is required for maintaining tissue homeostasis, including in the reproductive system, but the underlying mechanisms on how LIN28A regulates germline progenitors remain unclear. Here, we dissected LIN28A-binding targets using high-throughput…
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Keywords:
mouse testes;
lin28a binds;
null mouse;
translation ... See more keywords
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Published in 2017 at "eNeuro"
DOI: 10.1523/eneuro.0388-17.2017
Abstract: Abstract Christianson syndrome (CS) is an X-linked disorder resulting from loss-of-function mutations in SLC9A6, which encodes the endosomal Na+/H+ exchanger 6 (NHE6). Symptoms include early developmental delay, seizures, intellectual disability, nonverbal status, autistic features, postnatal…
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Keywords:
neurodegenerative pathology;
christianson syndrome;
pathology;
nhe6 null ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010554
Abstract: The complete molecular mechanisms underlying the pathophysiology of Alzheimer’s disease (AD) remain to be elucidated. Recently, microRNA-455-3p has been identified as a circulating biomarker of early AD, with increased expression in post-mortem brain tissue of…
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Keywords:
null mouse;
microrna 455;
455 null;
mir 455 ... See more keywords