Expansion of gastric intestinal metaplasia with copy number aberrations contributes to field cancerization.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-1523
Abstract: Intestinal metaplasia (IM) is a risk factor for gastric cancer following infection with Helicobacter pylori. To explore the susceptibility of pure gastric IM to cancer development, we investigated genetic alterations in single IM gastric glands.… read more here.
Keywords: copy number; number aberrations; cancer; intestinal metaplasia ... See more keywords
Neutron-induced Rat Mammary Carcinomas Are Mainly of Luminal Subtype and Have Multiple Copy Number Aberrations
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DOI: 10.21873/anticanres.13222
Abstract: Background/Aim: Neutrons are used as a type of high linear energy transfer (LET) radiation and they have stronger carcinogenic effects compared to low LET radiation. We sought to clarify the features of mammary carcinomas for… read more here.
Keywords: carcinomas; mammary carcinomas; copy number; number aberrations ... See more keywords
Signatures of Discriminative Copy Number Aberrations in 31 Cancer Subtypes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.654887
Abstract: Copy number aberrations (CNA) are one of the most important classes of genomic mutations related to oncogenetic effects. In the past three decades, a vast amount of CNA data has been generated by molecular-cytogenetic and… read more here.
Keywords: cancer; cna; copy number; number aberrations ... See more keywords