The number needed to treat adjusted for explanatory variables in regression and survival analysis: Theory and application
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in Medicine"
DOI: 10.1002/sim.9418
Abstract: The number needed to treat (NNT) is an efficacy index commonly used in randomized clinical trials. The NNT is the average number of treated patients for each undesirable patient outcome, for example, death, prevented by… read more here.
Keywords: explanatory variables; regression; number needed; needed treat ... See more keywords
Appraising esketamine nasal spray for the management of treatment-resistant depression in adults: Number needed to treat, number needed to harm, and likelihood to be helped or harmed.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2020.03.106
Abstract: INTRODUCTION This post hoc study assessed the evidence-base for esketamine nasal spray for management of treatment-resistant depression (TRD) using number needed to treat (NNT), number needed to harm (NNH), and likelihood to be helped or… read more here.
Keywords: nasal spray; esketamine nasal; esketamine; number needed ... See more keywords
The number needed to treat for net effect (NNTnet) as a metric for measuring combined benefits and harms.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of clinical epidemiology"
DOI: 10.1016/j.jclinepi.2020.05.031
Abstract: Calculating the number needed to treat (NNT) has been widely used to help understand treatment effect results of randomized controlled trials (RCTs). Combined benefit-and-harm profiles from RCT results have to be taken into account to… read more here.
Keywords: nntnet; effect; net effect; number needed ... See more keywords
Number needed to treat for direct oral anticoagulants over warfarin in atrial fibrillation.
Sign Up to like & getrecommendations! Published in 2017 at "Medicina clinica"
DOI: 10.1016/j.medcli.2017.03.039
Abstract: RE-LY2 Ensayo clínico 18.113 Dabigatrán 150 mg/12 h vs. warfarina 1,11 vs. 1 HR: 0,66 p < 0,001 Dabigatrán 110 mg/12 h vs. warfarina 1,53 vs. 1 HR: 0,91 p = 0,34 ROCKET-AF3 Ensayo clínico… read more here.
Keywords: dabigatr 150; ensayo nico; warfarina; 150 warfarina ... See more keywords
Lemborexant and Daridorexant for the Treatment of Insomnia: An Indirect Comparison, Using Number Needed to Treat, Number Needed to Harm, and Likelihood to Be Helped or Harmed
Sign Up to like & getrecommendations! Published in 2023 at "CNS Spectrums"
DOI: 10.1017/s1092852923002183
Abstract: Abstract Background To describe lemborexant and daridorexant for insomnia treatment using number needed to treat (NNT), number needed to harm (NNH), and likelihood to be helped or harmed (LHH). Methods Dichotomous outcomes were identified from… read more here.
Keywords: number needed; number; needed harm; using number ... See more keywords
The number needed to teach: A framework for health professions education
Sign Up to like & getrecommendations! Published in 2024 at "Medical Teacher"
DOI: 10.1080/0142159x.2024.2436445
Abstract: Abstract What is the educational challenge? Health professions education is continually limited by financial resources with increasing demands for accountability. Judicious resource allocation across competing demands rests on frameworks for analyzing and comparing costs and… read more here.
Keywords: needed teach; number; health professions; professions education ... See more keywords
The efficacy of zuranolone in postpartum depression and major depressive disorder: a review & number needed to treat (NNT) analysis
Sign Up to like & getrecommendations! Published in 2024 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2023.2298340
Abstract: ABSTRACT Introduction Major depressive disorder (MDD) is a common and debilitating mental illness. Postpartum depression (PPD) impacts women globally and is one of the most common complications of childbirth that is underdiagnosed and undertreated, adversely… read more here.
Keywords: postpartum depression; depressive disorder; number needed; major depressive ... See more keywords
Letter to the editor: consideration on: ‘What is the risk of cardiovascular events in osteoporotic patients treated with romosozumab?’ by Reid I.R
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2023.2173737
Abstract: We read with great interest the editorial by I.R. Reid published in Expert Opinion on Drug Safety [1]. The Author addressed cardiovascular safety of romosozumab. He thoroughly discussed data from the ARCH trial [2] that… read more here.
Keywords: romosozumab; number needed; alendronate; risk ... See more keywords
0350 Daridorexant in patients with insomnia disorder: number needed to treat, number needed to harm & likelihood to be helped or harmed
Sign Up to like & getrecommendations! Published in 2023 at "SLEEP"
DOI: 10.1093/sleep/zsad077.0350
Abstract: Patients with insomnia disorder have difficulty initiating or maintaining sleep and have impaired daytime functioning. Daridorexant is a dual orexin receptor antagonist approved for the treatment of insomnia. This analysis reports the number needed to… read more here.
Keywords: number needed; number; patients insomnia; insomnia disorder ... See more keywords
The number needed to biopsy for cutaneous melanoma in academic dermatology clinics
Sign Up to like & getrecommendations! Published in 2024 at "Melanoma Research"
DOI: 10.1097/cmr.0000000000000979
Abstract: A standard metric for melanoma detection is the number needed to biopsy (NNB). This metric has been used to evaluate practicing dermatologists, dermatology advanced practice professionals, and primary care providers. This metric, however, has rarely… read more here.
Keywords: number; needed biopsy; covid; nnb ... See more keywords
Number (of Whom?) Needed to Treat (with What?): Exposures, Population Interventions, and the Number Needed to Treat.
Sign Up to like & getrecommendations! Published in 2019 at "Epidemiology"
DOI: 10.1097/ede.0000000000001061
Abstract: The number needed to treat (NNT) is a widely used measure of the potential impact of a treatment or intervention, but it is often calculated and discussed in ways which oversimplify critical issues. Specifically, the… read more here.
Keywords: number needed; treat exposures; exposures population; needed treat ... See more keywords