Dearomatization of Heteroarenium Salts with ArBpin Reagents. Application to the Total Synthesis of a Nuphar Alkaloid.
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DOI: 10.1021/acs.orglett.2c00976
Abstract: Rhodium-catalyzed enantioselective addition of aryl and heteroaryl boron pinacol esters to pyridinium and quinolinium salts is developed for the synthesis of enantioenrichred dihydroheteroarenes. The methodology has enabled the synthesis of 2-heteroaryl-substituted dihydropyridines in high yield… read more here.
Keywords: dearomatization heteroarenium; heteroarenium salts; nuphar alkaloid; synthesis ... See more keywords