Articles with "nutrient gradients" as a keyword



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An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients

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Published in 2021 at "Communications Biology"

DOI: 10.1038/s42003-021-01954-0

Abstract: The tumor microenvironment (TME) is multi-cellular, spatially heterogenous, and contains cell-generated gradients of soluble molecules. Current cell-based model systems lack this complexity or are difficult to interrogate microscopically. We present a 2D live-cell chamber that… read more here.

Keywords: tumorigenesis; live cell; model; cell generated ... See more keywords