Lysosome Inhibition Reduces Basal and Nutrient-Induced Fat Accumulation in Caenorhabditis elegans
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DOI: 10.14348/molcells.2022.0073
Abstract: A long-term energy nutritional imbalance fundamentally causes the development of obesity and associated fat accumulation. Lysosomes, as nutrient-sensing and lipophagy centers, critically control cellular lipid catabolism in response to nutrient deprivation. However, whether lysosome activity… read more here.
Keywords: induced fat; basal nutrient; fat accumulation; accumulation ... See more keywords
The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion
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DOI: 10.3390/metabo12050420
Abstract: The enteroendocrine system of the gut regulates energy homeostasis through the release of hormones. Of the gut-derived hormones, GLP-1 is particularly interesting, as analogs of the hormone have proven to be highly effective for the… read more here.
Keywords: glp secretion; mechanisms nutrient; secretion; nutrient induced ... See more keywords