Nutrient Stress Small-Molecule Screening Platform for Escherichia coli.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7847-2_1
Abstract: Clinically approved antibiotics target a narrow spectrum of cellular processes, namely cell wall synthesis, DNA replication, and protein synthesis. Numerous screens have been designed to identify inhibitors that target one of these cellular processes. Indeed,… read more here.
Keywords: escherichia coli; coli nutrient; nutrient stress; stress ... See more keywords
Rerouting of Metabolism into Desired Cellular Products by Nutrient Stress: Fluxes Reveal the Selected Pathways in Cyanobacterial Photosynthesis.
Sign Up to like & getrecommendations! Published in 2018 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.8b00116
Abstract: Boosting cellular growth rates while redirecting metabolism to make desired products are the preeminent goals of gene engineering of photoautotrophs, yet so far these goals have been hardly achieved owing to lack of understanding of… read more here.
Keywords: metabolism; metabolism desired; nutrient stress; desired cellular ... See more keywords
SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.1101/2024.02.27.582293
Abstract: De novo lipogenesis is associated with the development of human diseases such as cancer, diabetes, and obesity. At the core of lipogenesis lies acetyl coenzyme A (CoA), a metabolite that plays a crucial role in… read more here.
Keywords: sirt2 mediated; nutrient stress; stress; k271 ... See more keywords
Metagenomic analysis reveals global-scale patterns of ocean nutrient limitation
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abe6301
Abstract: Genomes reveal nutrient stress patterns Within the surface ocean, nitrogen, iron, and phosphorous can all be limiting nutrients for phytoplankton depending on location. Ustick et al. used the prevalence of Prochlorococcus genes involved in nutrient… read more here.
Keywords: limitation; global ocean; ocean nutrient; nutrient stress ... See more keywords
Nutrient Stress-Dysregulated Antisense lncRNA GLS-AS Impairs GLS-Mediated Metabolism and Represses Pancreatic Cancer Progression.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-0419
Abstract: Cancer cells are known to undergo metabolic reprogramming, such as glycolysis and glutamine addiction, to sustain rapid proliferation and metastasis. It remains undefined whether long noncoding RNAs (lncRNA) coordinate the metabolic switch in pancreatic cancer.… read more here.
Keywords: gls; cancer; myc; nutrient stress ... See more keywords
Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity.
Sign Up to like & getrecommendations! Published in 2024 at "Cancer research"
DOI: 10.1158/0008-5472.can-23-2700
Abstract: Cancer stem/tumor-initiating cells display stress tolerance and metabolic flexibility to survive in a harsh environment with limited nutrient and oxygen availability. The molecular mechanisms underlying this phenomenon could provide targets to prevent metabolic adaptation and… read more here.
Keywords: cancer; upregulation; nutrient stress; lung cancer ... See more keywords
Overcoming Nutrient Stress: Integrin αvβ3-Driven Metabolic Adaptation Supports Tumor Initiation.
Sign Up to like & getrecommendations! Published in 2024 at "Cancer research"
DOI: 10.1158/0008-5472.can-24-0453
Abstract: Nutrient stress accompanies several stages of tumor progression, including metastasis formation. Metabolic reprogramming is a hallmark of cancer, and it has been associated with stress tolerance and anchorage-independent cell survival. Adaptive responses are required to… read more here.
Keywords: cancer; tumor initiation; nutrient stress;
Genome Editing Targets for Improving Nutrient Use Efficiency and Nutrient Stress Adaptation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.900897
Abstract: In recent years, the development of RNA-guided genome editing (CRISPR-Cas9 technology) has revolutionized plant genome editing. Under nutrient deficiency conditions, different transcription factors and regulatory gene networks work together to maintain nutrient homeostasis. Improvement in… read more here.
Keywords: genome editing; nutrient use; nutrient stress; efficiency ... See more keywords
The Ubiquitin Proteasome System and Nutrient Stress Response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.867419
Abstract: Plants utilize different molecular mechanisms, including the Ubiquitin Proteasome System (UPS) that facilitates changes to the proteome, to mitigate the impact of abiotic stresses on growth and development. The UPS encompasses the ubiquitination of selected… read more here.
Keywords: ubiquitin proteasome; nutrient stress; system nutrient; proteasome system ... See more keywords
Influence of Nutrient-Stress Conditions on Chlorella vulgaris Biomass Production and Lipid Content
Sign Up to like & getrecommendations! Published in 2021 at "Catalysts"
DOI: 10.3390/catal11050573
Abstract: Microalgal biomass and its cellular components are used as substrates for the production of fuels. A valuable group among the components of microalgal biomass is lipids, which act as a precursor for the production of… read more here.
Keywords: lipid content; stress conditions; production; biomass ... See more keywords
Plant DNA Methylation Responds to Nutrient Stress
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13060992
Abstract: Nutrient stress as abiotic stress has become one of the important factors restricting crop yield and quality. DNA methylation is an essential epigenetic modification that can effectively regulate genome stability. Exploring DNA methylation responses to… read more here.
Keywords: stress; dna methylation; nutrient stress; plant ... See more keywords