Bioreducible polymer-mediated delivery of oncolytic adenovirus can attenuate antiviral immune response and concurrently enhance the induction of antitumor immune response to effectively prevent metastasis.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00200k
Abstract: Oncolytic virotherapy is a highly promising and novel treatment modality for cancer. Several clinical trials with oncolytic viruses have illustrated that the potent antitumor efficacy of these viruses may rely on the efficient induction of… read more here.
Keywords: oad; antitumor; level; immune response ... See more keywords
Abstract 692: OAd-mediated SA-4-1BBL fused to HPV-16 E7 elicits specific antitumor efficacy in syngeneic mouse lung cancer model
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DOI: 10.1158/1538-7445.am2023-692
Abstract: Introduction: Human papillomaviruses (HPVs) are responsible for about 25% of cancer cases worldwide. HPV-16 E7 antigen is a tumor-associated antigen (TAA) commonly expressed in HPV-induced tumors; however, it has low immunogenicity. The interaction of 4-1BBL… read more here.
Keywords: oad; antitumor; model; 1bbl fused ... See more keywords
Outpatient Antibiotic Dispensing for the Population with Government Health Insurance in Syria in 2018–2019
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DOI: 10.3390/antibiotics9090570
Abstract: Little is known about antibiotic uses at the population level in Syria. The aim of our study is to present outpatient antibiotic dispensing (OAD) patterns and rates for patients with health insurance in the parts… read more here.
Keywords: oad; antibiotic dispensing; outpatient antibiotic; health insurance ... See more keywords