Organic anion-transporting polypeptide 1a4-mediated heterogeneous distribution of sulforhodamine-101 in rat hepatic lobules.
Sign Up to like & getrecommendations! Published in 2019 at "Drug metabolism and pharmacokinetics"
DOI: 10.1016/j.dmpk.2019.04.001
Abstract: It has been known that organic anion-transporting polypeptides (Oatps) involve hepatic transports several organic anionic compounds and drugs. This study aimed to investigate sulforhodamine-101 (SR-101) distribution in the rat liver, determine the molecules responsible for… read more here.
Keywords: anion transporting; rat; organic anion; rat hepatic ... See more keywords
Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice
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DOI: 10.1124/dmd.117.079483
Abstract: Among organic anion transporting polypeptide (Oatp) family transporters expressed in the rodent liver, such as Oatp1a1, Oatp1a4, Oatp1b2, and Oatp2b1, Oatp1a4 has a unique character to recognize neutral cardiac glycosides as a substrate in addition… read more here.
Keywords: anion transporting; cardiac glycosides; organic anion; slco1a4 mice ... See more keywords