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OATP1B3 (699G>A) and CYP2C9*2, *3 significantly influenced the transport and metabolism of glibenclamide and glipizide

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1 Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-36212-7

Abstract: Glibenclamide and glipizide show large substantial inter-individual variation in clinical efficacy, which may be resulted from the genetic differences of metabolic enzymes and transporters in individuals. This study purposed to investigate the effect of OATP1B3… read more here.

Keywords: metabolism glibenclamide; glipizide; transport metabolism; oatp1b3 699g ... See more keywords