Lipid Metabolism is Closely Associated with Normal Testicular Growth Based on Global Transcriptome Profiles in Normal and Underdeveloped Testis of Obese Zucker (fa/fa) Rats
Sign Up to like & getrecommendations! Published in 2017 at "Lipids"
DOI: 10.1007/s11745-017-4298-2
Abstract: Zucker (fa/fa) obese rats often have non-identical and differently sized paired testes, leaving one testis underdeveloped. Our earlier study found that the underdeveloped testes, > 30% smaller than the normal ones, have a selective decrease in docosapentaenoic… read more here.
Keywords: obese zucker; testis; zucker; metabolism ... See more keywords
Dietary intake of cod protein beneficially affects concentrations of urinary markers of kidney function and results in lower urinary loss of amino acids in obese Zucker fa/fa rats
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Nutrition"
DOI: 10.1017/s0007114518002076
Abstract: Abstract Obesity increases the risk for developing kidney disease, and protection of kidneys through changes in diet should be investigated. Fish intake has been associated with reduced risk of developing kidney disease; therefore, we wanted… read more here.
Keywords: protein; obese zucker; zucker; zucker rats ... See more keywords
Effects of Prolonged Energy Restriction and Dietary Protein on Muscle Protein Synthesis and Proteome Dynamics in Obese Zucker Rats
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DOI: 10.1093/cdn/nzaa049_063
Abstract: High protein (HP) diets during short-term energy restriction (ER) attenuate energy-mediated reductions in muscle protein synthesis (MPS). MPS-adaptive responses to HP diets during prolonged ER are not well described. This study examined the effects of… read more here.
Keywords: protein; obese zucker; muscle protein; energy ... See more keywords
Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abh1316
Abstract: Circadian rhythms play a critical role in regulating metabolism, including daily cycles of feeding/fasting. Glucokinase (GCK) is central for whole-body glucose homeostasis and oscillates according to a circadian clock. GCK activators (GKAs) effectively reduce hyperglycemia,… read more here.
Keywords: obese zucker; feeding periods; glucokinase; zucker rats ... See more keywords
Alpha-linolenic acid and linoleic acid differentially regulate the skeletal muscle secretome of obese Zucker rats.
Sign Up to like & getrecommendations! Published in 2018 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00038.2018
Abstract: Evidence shows that proteins secreted from skeletal muscle influence a broad range of metabolic signaling pathways. We previously reported that essential polyunsaturated fatty acids (PUFA) improved whole-body glucose homeostasis in obese Zucker rats; however, the… read more here.
Keywords: skeletal muscle; obese zucker; muscle secretome; muscle ... See more keywords
Simvastatin Does Not Affect Nitric Oxide Generation Increased by Sesame Oil in Obese Zucker Rats
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/5413423
Abstract: Current treatments for cardiovascular and obesity-associated diseases, such as statin therapy, may be associated with several side effects. Products from food sources with polyphenolic compounds may represent promising agents in the treatment of cardiovascular and… read more here.
Keywords: sesame oil; obese zucker; zucker rats; nitric oxide ... See more keywords
Insulin-Regulated Aminopeptidase Inhibition Ameliorates Metabolism in Obese Zucker Rats
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.586225
Abstract: The aim of our study was to determine the influence of inhibition of insulin-regulated aminopeptidase/oxytocinase (IRAP) on glucose tolerance and metabolism of skeletal muscle and visceral adipose tissue in obese Zucker rats. Obese Zucker rats… read more here.
Keywords: obese zucker; zucker; metabolism; zucker rats ... See more keywords
Long-Term Soy Protein Isolate Consumption Reduces Liver Steatosis Through Changes in Global Transcriptomics in Obese Zucker Rats
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2020.607970
Abstract: To determine how soy protein isolate (SPI) ameliorated liver steatosis in male obese Zucker rats, we conducted global transcriptomic expression (RNAseq) analysis on liver samples of male rats fed either the SPI or a control… read more here.
Keywords: liver steatosis; fed rats; obese zucker; spi ... See more keywords
Feeding of Hermetia illucens Larvae Meal Attenuates Hepatic Lipid Synthesis and Fatty Liver Development in Obese Zucker Rats
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15020287
Abstract: The present study tested the hypothesis that dietary insect meal from Hermetia illucens (HI) larvae attenuates the development of liver steatosis and hyperlipidemia in the obese Zucker rat. To test the hypothesis, a 4-week trial… read more here.
Keywords: obese zucker; zucker; group; larvae meal ... See more keywords
Plasma proteome alterations in prediabetic, obese Zucker rats - possible cardiovascular risk implications.
Sign Up to like & getrecommendations! Published in 2022 at "General physiology and biophysics"
DOI: 10.4149/gpb_2022043
Abstract: Hyperphagia and obesity, which underlie metabolic syndrome, have been linked to multiple health complications and increased mortality. Here, we investigate the differences in plasma proteome between obese and lean Zucker rats in order to identify… read more here.
Keywords: obese zucker; zucker; plasma proteome; alterations prediabetic ... See more keywords