Characterizing the Role of Calcium Sensing Receptor in the Progression of Obesity-Mediated Aggressive Prostate Cancer Phenotype
Sign Up to like & getrecommendations! Published in 2023 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2023.2176198
Abstract: Abstract Obesity increases the risk of advanced prostate cancer (PCa). The calcium sensing receptor (CaSR) has been shown to be responsive to obesity-mediated cytokines and is upregulated in metastatic PCa. This study used a novel… read more here.
Keywords: prostate cancer; calcium sensing; expression; obesity mediated ... See more keywords
Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/6054361
Abstract: Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the predominant Nox enzymes expressed… read more here.
Keywords: obesity mediated; bone; bone remodeling; mice ... See more keywords
Obesity-Mediated Immune Modulation: One Step Forward, (Th)2 Steps Back
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.932893
Abstract: Over the past decades, the relationship between the immune system and metabolism has become a major research focus. In this arena of immunometabolism the capacity of adipose tissue to secrete immunomodulatory molecules, including adipokines, within… read more here.
Keywords: immune responses; mediated immune; obesity mediated; modulation one ... See more keywords