Abstract P3-03-12: Obesity promotes the activation of genes and pathways in tumor associated breast fat
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DOI: 10.1158/1538-7445.sabcs19-p3-03-12
Abstract: Tumor-associated adipocytes play an active role in breast tumor progression. Moreover, obesity has been established as a risk factor in cancer-related mortality. The altered expression of genes and signaling pathways in breast adipose as a… read more here.
Keywords: obesity promotes; breast; tumor associated; cancer ... See more keywords
Obesity Promotes Metabolic Rewiring That Starves Cytotoxic T Cells.
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DOI: 10.1158/2159-8290.cd-rw2020-183
Abstract: In mice, obesity remodeled TME metabolism, reducing infiltration by CD8+ T cells and antitumor immunity. read more here.
Keywords: metabolic rewiring; rewiring starves; starves cytotoxic; promotes metabolic ... See more keywords
Obesity Promotes EAE Through IL-6 and CCL-2-Mediated T Cells Infiltration
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DOI: 10.3389/fimmu.2019.01881
Abstract: Growing evidence suggests that obesity is associated with the susceptibility and disease severity of multiple sclerosis. The chronic inflammation induced by obesity is believed to contribute to this process. However, the immune mechanisms connecting obesity… read more here.
Keywords: ccl mediated; cells infiltration; eae ccl; obesity promotes ... See more keywords