The effects of an obesogenic diet on behavior and cognition in zebrafish (Danio rerio): Trait average, variability, repeatability, and behavioral syndromes
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.9511
Abstract: Abstract The obesity epidemic, largely driven by the accessibility of ultra‐processed high‐energy foods, is one of the most pressing public health challenges of the 21st century. Consequently, there is increasing concern about the impacts of… read more here.
Keywords: behavior cognition; behavioral syndromes; obesogenic diet; danio rerio ... See more keywords
Effects of estradiol supplementation on the brain transcriptome of old rhesus macaques maintained on an obesogenic diet.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00453-8
Abstract: Obesity, the cessation of ovarian steroids with menopause, and age are risk factors for mood disorders, dementia, and Alzheimer's disease (AD). However, immediate hormone therapy (HT) after menopause may have beneficial effects in different brain… read more here.
Keywords: effects estradiol; rhesus macaques; obesogenic diet; brain ... See more keywords
Chronic chemogenetic manipulation of ventral pallidum targeted neurons in male rats fed an obesogenic diet
Sign Up to like & getrecommendations! Published in 2022 at "Brain Research"
DOI: 10.1016/j.brainres.2022.147886
Abstract: Current treatments for obesity do not reliably reduce body weight over time. New interventional strategies, including chemogenetics, carry promise based on preclinical animal studies. Here, we focused on the ventral pallidum (VP) due to its… read more here.
Keywords: targeted neurons; ventral pallidum; obesogenic diet; chemogenetic manipulation ... See more keywords
Short-term exposure to an obesogenic diet during adolescence elicits anxiety-related behavior and neuroinflammation: modulatory effects of exogenous neuregulin-1
Sign Up to like & getrecommendations! Published in 2022 at "Translational Psychiatry"
DOI: 10.1038/s41398-022-01788-2
Abstract: Childhood obesity leads to hippocampal atrophy and altered cognition. However, the molecular mechanisms underlying these impairments are poorly understood. The neurotrophic factor neuregulin-1 (NRG1) and its cognate ErbB4 receptor play critical roles in hippocampal maturation… read more here.
Keywords: neuroinflammation; exposure; short term; obesogenic diet ... See more keywords
The miRNA‐143‐3p–Sox6–Myh7 pathway is altered in obesogenic diet‐induced cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Physiology"
DOI: 10.1113/ep090315
Abstract: What is the central question of this study? What is the effect of an obesogenic diet on the expression of microRNAs (miRNAs) involved in cardiac hypertrophy in female mice? What is the main finding and… read more here.
Keywords: hypertrophy; 143 sox6; cardiac hypertrophy; obesogenic diet ... See more keywords
Maternal obesogenic diet induces endometrial hyperplasia, an early hallmark of endometrial cancer, in a diethylstilbestrol mouse model
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0186390
Abstract: Thirty-eight percent of US adult women are obese, meaning that more children are now born of overweight and obese mothers, leading to an increase in predisposition to several adult onset diseases. To explore this phenomenon,… read more here.
Keywords: maternal obesogenic; obesogenic diet; endometrial cancer; mouse model ... See more keywords
Effects of an obesogenic diet on the oviduct depend on the duration of feeding
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0275379
Abstract: Research question How long does it take for an obesogenic (high-fat/high-sugar, HF/HS) diet to influence the oviductal microenvironment? What are the affected cellular pathways and are they dependent on the genetic background of the mouse… read more here.
Keywords: stress; diet oviduct; effects obesogenic; oviduct depend ... See more keywords
Impacts of Diet and Exercise on Maternal Gut Microbiota Are Transferred to Offspring
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2018.00716
Abstract: Background: It is well established that maternal exercise during pregnancy improves metabolic outcomes associated with obesity in mothers and offspring, however, its effects on the gut microbiota of both mother and offspring, are unknown. Here,… read more here.
Keywords: control; obesogenic diet; exercise; gut microbiota ... See more keywords
Effects of Resveratrol Administration in Liver Injury Prevention as Induced by an Obesogenic Diet: Role of Ruminococcaceae
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10081797
Abstract: Gut microbiota dysbiosis has been described in several metabolic disruptions, such as non-alcoholic fatty liver disease (NAFLD). Administration of resveratrol has been claimed to elicit benefits against NAFLD along with modulating gut microbiota composition. This… read more here.
Keywords: administration; gut microbiota; resveratrol administration; effects resveratrol ... See more keywords
Obesogenic Diet-Induced Neuroinflammation: A Pathological Link between Hedonic and Homeostatic Control of Food Intake
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021468
Abstract: Obesity-induced neuroinflammation is a chronic aseptic central nervous system inflammation that presents systemic characteristics associated with increased pro-inflammatory cytokines such as interleukin 1 beta (IL-1β) and interleukin 18 (IL-18) and the presence of microglia and… read more here.
Keywords: neuroinflammation; intake obesogenic; induced neuroinflammation; control ... See more keywords
Understanding the Long-Lasting Effects of Fetal Nutrient Restriction versus Exposure to an Obesogenic Diet on Islet-Cell Mass and Function
Sign Up to like & getrecommendations! Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11080514
Abstract: Early life represents a window of phenotypic plasticity. Thus, exposure of the developing fetus to a compromised nutritional environment can have long term consequences for their health. Indeed, undernutrition or maternal intake of an obesogenic… read more here.
Keywords: understanding long; islet; obesogenic diet; versus ... See more keywords