Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114714
Abstract: Ovarian toxicity and infertility are major side effects of cancer therapy in young female cancer patients. We and others have previously demonstrated that doxorubicin (DOX), one of the most widely used chemotherapeutic chemicals, has a… read more here.
Keywords: dox induced; overactivation; obliterates mouse; follicle ... See more keywords