Shedding light on dark genes: enhanced targeted resequencing by optimizing the combination of enrichment technology and DNA fragment length
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DOI: 10.1038/s41598-020-66331-z
Abstract: The exome contains many obscure regions difficult to explore with current short-read sequencing methods. Repetitious genomic regions prevent the unique alignment of reads, which is essential for the identification of clinically-relevant genetic variants. Long-read technologies… read more here.
Keywords: dna fragment; dna; obscure regions; shedding light ... See more keywords