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   Articles with "obstructive hypertrophic" as a keyword



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Perioperative Amiodarone to Prevent Atrial fibrillation after Septal Myectomy in obstrUctive hypeRtroPHic cardiomyopathy.

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recommendations! Published in 2021 at "ESC heart failure"

DOI: 10.1002/ehf2.13662

Abstract: AIMS Amiodarone reduces the incidence of atrial fibrillation (AF) following coronary artery bypass surgery; however, the benefit of perioperative amiodarone in patients undergoing septal myectomy (SM) for obstructive hypertrophic cardiomyopathy (oHCM) has not been studied.… read more here.

Keywords: atrial fibrillation; perioperative amiodarone; amiodarone; septal myectomy ... See more keywords
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Effect of beta‐blocker therapy on the response to mavacamten in patients with symptomatic obstructive hypertrophic cardiomyopathy

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recommendations! Published in 2022 at "European Journal of Heart Failure"

DOI: 10.1002/ejhf.2737

Abstract: In the EXPLORER‐HCM trial, mavacamten improved exercise capacity and symptoms in patients with obstructive hypertrophic cardiomyopathy (oHCM). Mavacamten effects on the primary endpoint, a composite of peak oxygen consumption (VO2) and New York Heart Association… read more here.

Keywords: beta blocker; hypertrophic cardiomyopathy; obstructive hypertrophic; beta ... See more keywords
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Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial

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recommendations! Published in 2020 at "The Lancet"

DOI: 10.1016/s0140-6736(20)31792-x

Abstract: BACKGROUND Cardiac muscle hypercontractility is a key pathophysiological abnormality in hypertrophic cardiomyopathy, and a major determinant of dynamic left ventricular outflow tract (LVOT) obstruction. Available pharmacological options for hypertrophic cardiomyopathy are inadequate or poorly tolerated… read more here.

Keywords: placebo; treatment; obstructive hypertrophic; nyha class ... See more keywords
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Early outcomes of septal myectomy for obstructive hypertrophic cardiomyopathy in children with Noonan syndrome.

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recommendations! Published in 2021 at "Seminars in thoracic and cardiovascular surgery"

DOI: 10.1053/j.semtcvs.2021.07.027

Abstract: Noonan syndrome (NS) is a genetic syndrome causing obstructive hypertrophic cardiomyopathy (HCM) in infants. Studies of cardiac surgery in pediatric HCM patients with NS (NS-HCM) are lacking. We aim to characterize the early disease course… read more here.

Keywords: noonan syndrome; hcm patients; hypertrophic cardiomyopathy; hcm ... See more keywords
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Frequency and clinicoeconomic impact of delays to definitive diagnosis of obstructive hypertrophic cardiomyopathy in the United States.

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recommendations! Published in 2023 at "Journal of medical economics"

DOI: 10.1080/13696998.2023.2208966

Abstract: AIMS The diagnostic history in the years leading up to the definitive diagnosis of patients with obstructive hypertrophic cardiomyopathy (HCM) has not been studied. METHODS Patients with a delay in the definitive diagnosis of obstructive… read more here.

Keywords: hypertrophic cardiomyopathy; obstructive hcm; obstructive hypertrophic; diagnosis ... See more keywords
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Infective endocarditis in obstructive hypertrophic cardiomyopathy: a case series and literature review

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recommendations! Published in 2020 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000001265

Abstract: To the Editor: Infective endocarditis (IE) is a rare complication of hypertrophic cardiomyopathy (HCM) that may lead to fatal outcomes if the infection is not effectively controlled. We report three cases of hypertrophic obstructive cardiomyopathy… read more here.

Keywords: obstructive hypertrophic; hypertrophic cardiomyopathy; infective endocarditis; endocarditis obstructive ... See more keywords
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Sex differences in clinical outcomes for obstructive hypertrophic cardiomyopathy in the USA: a retrospective observational study of administrative claims data

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recommendations! Published in 2022 at "BMJ Open"

DOI: 10.1136/bmjopen-2021-058151

Abstract: Objectives To evaluate sex differences in demographic and clinical characteristics, treatments and outcomes for patients with diagnosed obstructive hypertrophic cardiomyopathy (oHCM) in the USA. Setting Retrospective observational study of administrative claims data from MarketScan Commercial… read more here.

Keywords: hypertrophic cardiomyopathy; obstructive hypertrophic; retrospective observational; fibrillation ... See more keywords
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Abstract 17141: Mavacamten Improves Left Ventricular Relaxation and Compliance in Obstructive Hypertrophic Cardiomyopathy Through Direct Myosin Modulation

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recommendations! Published in 2018 at "Circulation"

DOI: 10.1161/circ.138.suppl_1.17141

Abstract: Introduction: Obstructive hypertrophic cardiomyopathy (oHCM) consists of a constellation of LV hypercontractility, LV outflow tract obstruction (LVOTO), and impaired relaxation, often resulting in dyspnea and reduced exercise capacity. In healthy dogs, the novel myosin modulator… read more here.

Keywords: relaxation; myosin; hypertrophic cardiomyopathy; compliance ... See more keywords
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Abstract 13590: Demographic and Clinical Characteristics of Patients With Obstructive Hypertrophic Cardiomyopathy in a Large, Nationwide Us Cohort

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recommendations! Published in 2020 at "Circulation"

DOI: 10.1161/circ.142.suppl_3.13590

Abstract: Background: Obstructive hypertrophic cardiomyopathy (oHCM) has mostly been studied in patients treated in advanced comprehensive Centers of Excellence (COE). Understanding the true prevalence of patients with oHCM in the general US population may improve the… read more here.

Keywords: obstructive hypertrophic; clinical characteristics; characteristics patients; cohort ... See more keywords
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Mavacamten, a First-in-Class Cardiac Myosin Inhibitor for Obstructive Hypertrophic Cardiomyopathy

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recommendations! Published in 2022 at "Annals of Pharmacotherapy"

DOI: 10.1177/10600280221117812

Abstract: Objective: To assess mavacamten’s role in hypertrophic cardiomyopathy treatment. Data Sources: In addition to clinical guidelines, package inserts, and general reviews, we searched PubMed using the term mavacamten from inception to June 11, 2022. Study… read more here.

Keywords: mavacamten first; hypertrophic cardiomyopathy; first class; obstructive hypertrophic ... See more keywords
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Surgical septal myectomy outcome for obstructive hypertrophic cardiomyopathy after alcohol septal ablation.

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recommendations! Published in 2021 at "Journal of thoracic disease"

DOI: 10.21037/jtd-20-2779

Abstract: Background Although surgical treatment of residual obstruction after alcohol septal ablation (ASA) is often challenging in patients with obstructive hypertrophic cardiomyopathy (OHCM) there are very few relevant clinical reports. Thus, outcomes of surgical septal myectomy… read more here.

Keywords: group; septal ablation; alcohol septal; hypertrophic cardiomyopathy ... See more keywords