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Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.28225
Abstract: Key Points Question Is obstructive sleep apnea (OSA) associated with brain white matter hyperintensities (WMHs)? Findings In this cohort study of 529 participants of the Study of Health in Pomerania-Trend baseline, a statistically significant association… read more here.
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Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.22999
Abstract: Key Points Question Is obstructive sleep apnea (OSA) associated with cognition and white matter (WM) integrity over time? Findings In this cohort study of 1110 participants, OSA was associated with impaired cognition and WM integrity… read more here.
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Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.39874
Abstract: This cohort study investigates the association of obstructive sleep apnea severity with risk of incident cerebral microbleeds in middle-aged and older adults in Korea. read more here.
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Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.756
Abstract: Obstructive sleep apnea syndrome (OSAS) is characterized by nocturnal intermittent hypoxemia and can increase the risk of Parkinson's disease. This study aimed to investigate the association between plasma α‐synuclein levels and hypoxia in the patients… read more here.
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Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1287
Abstract: Intermittent hypoxia and sleep fragmentation are critical pathophysiological processes involved in obstructive sleep apnea‐hypopnea syndrome (OSAHS). Those manifestations independently affect similar brain regions and contribute to OSAHS‐related comorbidities that are known to be related to… read more here.
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Published in 2024 at "Brain and Behavior"
DOI: 10.1002/brb3.3541
Abstract: Using correlation tractography, this study aimed to find statistically significant correlations between white matter (WM) tracts in participants with obstructive sleep apnea (OSA) and OSA severity. We hypothesized that changes in certain WM tracts could… read more here.
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Published in 2024 at "Brain and Behavior"
DOI: 10.1002/brb3.70026
Abstract: Obstructive sleep apnea (OSA) is a prevalent sleep disorder that is associated with structural brain damage and cognitive impairment. The hypothalamus plays a crucial role in regulating sleep and wakefulness. We aimed to evaluate hypothalamic… read more here.
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Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70462
Abstract: Observational studies have associated obstructive sleep apnea (OSA) with a higher risk of various cancers; however, causal relationships have not yet been definitively established. read more here.
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Published in 2018 at "Brain and Behavior"
DOI: 10.1002/brb3.994
Abstract: Brain structural injury and metabolic deficits in the hippocampus and caudate nuclei may contribute to cognitive and emotional deficits found in obstructive sleep apnea (OSA) patients. If such contributions exist, resting‐state interactions of these subcortical… read more here.
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Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.7198
Abstract: Fatigue and sleep disorders are prevalent in cancer patients. Obstructive sleep apnea (OSA) commonly causes excessive daytime sleepiness (EDS) and fatigue. We hypothesize that treating cancer patients with OSA using positive airway pressure (PAP) will… read more here.
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Published in 2017 at "Clinical Cardiology"
DOI: 10.1002/clc.22738
Abstract: Heart failure (HF) readmission rates have become an increasingly important quality metric since the advent of the Hospital Readmissions Reduction Program. Despite many well‐intentioned efforts to reduce readmissions, clinicians continue to struggle with the problem… read more here.