Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles
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DOI: 10.1038/s41598-020-64349-x
Abstract: Cognitive impairment is a well-known complication of diabetes mellitus (DM). Microvascular compromise was described one DM complication. Recently we showed blood brain barrier (BBB) permeability and memory loss are associated with diminution of tight junctions… read more here.
Keywords: occludin claudin; end products; glycation end; advanced glycation ... See more keywords
Specific role of the tight junction proteins occludin and claudin-5 on the blood–brain barrier during Listeria monocytogenes infection
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DOI: 10.21521/mw.6416
Abstract: To investigate the blood-brain barrier (BBB) permeability of mice after Listeria monocytogenes infection for further study on the mechanism of L. monocytogenes crossing the BBB, a mouse model was established and Evans blue assay was… read more here.
Keywords: occludin claudin; blood brain; expression; monocytogenes infection ... See more keywords