The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso‐occlusive crises
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DOI: 10.1002/ajh.24750
Abstract: Sickle Cell Disease (SCD) is a painful, lifelong hemoglobinopathy inherited as a missense point mutation in the hemoglobin (Hb) beta‐globin gene. This disease has significant impact on quality of life and mortality, thus a substantial… read more here.
Keywords: occlusive crises; heme; vaso occlusive; disease ... See more keywords
Real‐World Evidence of Crizanlizumab Showing Reductions in Vaso‐Occlusive Crises and Opioid Usage in Sickle Cell Disease
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DOI: 10.1111/ejh.14323
Abstract: Access to crizanlizumab, a disease‐modifying therapy for sickle cell disease (SCD), was provided through a managed access program (MAP, NCT03720626). The present analysis evaluated the impact of 12 months of crizanlizumab treatment on vaso‐occlusive crises (VOCs),… read more here.
Keywords: disease; cell disease; occlusive crises; vaso occlusive ... See more keywords