Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis.
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DOI: 10.1016/j.joca.2019.04.012
Abstract: OBJECTIVE Alkaptonuria (AKU) is a rare, inherited disorder of tyrosine metabolism, where patients are unable to breakdown homogentisic acid (HGA), which increases systemically over time. It presents with a clinical triad of features; HGA in… read more here.
Keywords: technique; ochronotic cartilage; non ochronotic; ochronosis ... See more keywords