Ochronotic pigmentation is caused by homogentisic acid and is the key event in alkaptonuria leading to the destructive consequences of the disease—A review
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DOI: 10.1002/jimd.12152
Abstract: Ochronosis is the process in alkaptonuria (AKU) that causes all the debilitating morbidity. The process involves selective deposition of homogentisic acid (HGA)‐derived pigment in tissues altering the properties of these tissues, leading to their failure.… read more here.
Keywords: pigmentation caused; homogentisic acid; ochronotic pigmentation; disease ... See more keywords