Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum in olfactory bulbectomized mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural medicines"
DOI: 10.1007/s11418-022-01609-2
Abstract: This study aims to clarify the bioactive constituents responsible for the anti-dementia effects of Ocimum sanctum Linn. ethanolic extract (OS) using olfactory bulbectomized (OBX) mice, an animal model of dementia. The effects of OS or… read more here.
Keywords: effects ocimum; anti dementia; responsible anti; dementia effects ... See more keywords
Effect of Ocimum sanctum and Crataegus pubescens aqueous extracts on obesity, inflammation, and glucose metabolism
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DOI: 10.1016/j.jff.2017.05.028
Abstract: Abstract This study aimed to evaluate the effect of Ocimum sanctum and Crataegus pubescens extracts on obesity, inflammation, and glucose metabolism in obese rats. Both extracts exerted anti-obesogenic effects, which was associated to increased fecal… read more here.
Keywords: sanctum; crataegus pubescens; sanctum crataegus; effect ... See more keywords
Green synthesized (Ocimum sanctum and Allium sativum) Ag-doped cobalt ferrite nanoparticles for antibacterial application
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DOI: 10.1016/j.vacuum.2018.12.021
Abstract: Abstract Cobalt ferrite and silver doped cobalt ferrite, AgxCo1−xFe2O4, (x = 0, 0.005, 0.01, 0.02) nanoparticles were synthesized through sol-gel auto-combustion technique via chemical and green synthesis (using the extract of tulsi seeds(Ocimum sanctum) and garlic cloves(Allium… read more here.
Keywords: prepared samples; cobalt ferrite; green synthesized; allium sativum ... See more keywords
Ocimum sanctum, Zingiber officinale, and Piper nigrum extracts and their effects on gut microbiota modulations (prebiotic potential), basal inflammatory markers and lipid levels: oral supplementation study in healthy rats
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DOI: 10.1080/13880209.2022.2033797
Abstract: Abstract Context Ocimum sanctum Linn (Labiatae) (OS), Zingiber officinale Rose (Zingiberaceae) (ZO), and Piper nigrum Linn (Piperaceae) (PN) are used in traditional medicine as immunomodulator, anti-inflammatory, and bioavailability enhancer agents. Objective Active phytoconstituents of OS,… read more here.
Keywords: gut microbiota; piper nigrum; extracts effects; effects gut ... See more keywords
Deciphering the anti-filarial potential of bioactive compounds from Ocimum sanctum: a combined experimental and computational study
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2132030
Abstract: Abstract Context The anthelminthic effect of Ocimum species (Lamiaceae) has been reported, however, its anti-filarial effect has not been explored to date. Objective This study evaluates the effect of Ocimum sanctum L. (OS) against lymphatic… read more here.
Keywords: bioactive compounds; effect; sanctum; anti filarial ... See more keywords
Ursolic acid rich Ocimum sanctum L leaf extract loaded nanostructured lipid carriers ameliorate adjuvant induced arthritis in rats by inhibition of COX-1, COX-2, TNF-α and IL-1: Pharmacological and docking studies
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DOI: 10.1371/journal.pone.0193451
Abstract: Background Ursolic acid (UA) is a promising molecule with anti-inflammatory, analgesic and potential anti-arthritic activity. Methods This study was undertaken to make formulation and evaluation of Ocimum sanctum L. leaf extract (OLE) loaded nano-structured lipid… read more here.
Keywords: anti arthritic; sanctum leaf; ursolic acid; formulation ... See more keywords
Ocimum sanctum [Tulsi] as a Potential Immunomodulator for the Treatment of Ischemic Injury in the Brain.
Sign Up to like & getrecommendations! Published in 2022 at "Current molecular medicine"
DOI: 10.2174/1566524023666221212155340
Abstract: Stroke causes brain damage and is one of the main reasons for death. Most survivors of stroke face long-term physical disabilities and cognitive dysfunctions. In addition, they also have persistent emotional and behavioral changes. The… read more here.
Keywords: brain; injury; tulsi; stroke ... See more keywords
Chemotherapeutic Role of Polyphenols Present in Ocimum Sanctum.
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DOI: 10.2174/1871520622666220516142839
Abstract: Ocimum sanctum is a sacred herb of India and is commonly known as 'Tulsi' or 'Holy Basil' in regional languages of the country. Various parts of O. sanctum are recognised to have remarkable therapeutic efficacy,… read more here.
Keywords: polyphenols present; present ocimum; sanctum; chemotherapeutic role ... See more keywords
Inhibitory Potential of the Ocimum sanctum Phytochemicals on Bruton’s Tyrosine Kinase, a Well-Known Drug Target for Treatment of Chronic Lymphocytic Leukemia: An In Silico Investigation
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28083287
Abstract: Chronic lymphocytic leukemia (CLL) is an incurable neoplasm of B-lymphocytes, which accounts for about one-third of all leukemias. Ocimum sanctum, an herbaceous perennial, is considered as one of the important sources of drugs for the… read more here.
Keywords: lymphocytic leukemia; phytochemicals sanctum; bruton tyrosine; chronic lymphocytic ... See more keywords
Bioprospective Role of Ocimum sanctum and Solanum xanthocarpum against Emerging Pathogen: Mycobacterium avium Subspecies paratuberculosis: A Review
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28083490
Abstract: Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, contagious, and typically life-threatening enteric disease of ruminants caused by a bacterium of the genus Mycobacterium, but it can also affect non-ruminant animals. MAP transmission occurs through… read more here.
Keywords: subspecies paratuberculosis; avium subspecies; mycobacterium; mycobacterium avium ... See more keywords
Ocimum Sanctum [Tulsi]—An Alternative Additional Livelihood Option for the Poor and Smallholder Farmers
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DOI: 10.3390/su11010227
Abstract: The scope of Tulsi (Ocimum sanctum) as an alternative crop and means of livelihood, particularly for the rural poor, has not been extensively explored. Tulsi is in much demand for its medicinal and aromatic properties,… read more here.
Keywords: tulsi; alternative additional; income; smallholder farmers ... See more keywords