Abstract 2580: Targeting chromatin in ovarian cancer stem cells
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-2580
Abstract: The dynamic organization of chromatin, governed by epigenetic modifiers, critically regulates cell plasticity and determines cell fate in both normal and malignant stem cells. We hypothesized that chromatin architecture plays a role in regulating transcriptional… read more here.
Keywords: cancer; chromatin; stem cells; ovarian cancer ... See more keywords
hPaf1/PD2 interacts with OCT3/4 to promote self-renewal of ovarian cancer stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14775
Abstract: Cancer stem cells (CSCs), which mediate drug resistance and disease recurrence in several cancers, are therapeutically relevant to ovarian cancer (OC), wherein approximately 80% of patients manifest with tumor recurrence. While there are several markers… read more here.
Keywords: pd2; ocscs; self renewal; cancer ... See more keywords