Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007687
Abstract: The transcription factor Oct1/Pou2f1 promotes poised gene expression states, mitotic stability, glycolytic metabolism and other characteristics of stem cell potency. To determine the effect of Oct1 loss on stem cell maintenance and malignancy, we deleted… read more here.
Keywords: oct1 pou2f1; colon; malignancy; colon malignancy ... See more keywords