Species specificity profiling of rat and human organic cation/carnitine transporter Slc22a5/SLC22A5 (Octn2/OCTN2).
Sign Up to like & getrecommendations! Published in 2017 at "Drug metabolism and pharmacokinetics"
DOI: 10.1016/j.dmpk.2016.08.005
Abstract: The purpose of this study was to characterize the uptake of carnitine, the physiological substrate, and the uptake of 3-(2,2,2-trimethylhydrazinium)propionate, a consensus substrate by rat Octn2 and human OCTN2 transporters as well as to characterize… read more here.
Keywords: slc22a5; octn2; rat human; carnitine ... See more keywords
Characterization of Exosomal SLC22A5 (OCTN2) carnitine transporter
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22170-7
Abstract: Exosomes are extracellular vesicles involved in cell-to-cell communication. Previous large scale proteomics revealed that they contain SLC proteins. However, no data on the function of exosomal SLCs is available, so far. An SLC localized in… read more here.
Keywords: slc22a5; carnitine transporter; octn2; carnitine ... See more keywords